Product Name:
ERK2 (182-188) pT185+pY187
Product Number:
pe-04azf00
Peptide Name: ERK2 (182-188) pT185+pY187
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases and for epitope mapping of phosphosite-specific antibodies. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. T185 and Y187 phosphorylation stimulate phosphotransferase activity and regulates cell growth, cell motility, cytoskeletal reorganization, transcription, protein conformation, intracellular location, protein degradation, and molecular association.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: GFL-pT-E-pY-V
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 986.88 Da
Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C