Product Name:
ErbB2 (1245-1251) pY1248
Product Number:
pe-04azd00
Peptide Name: ErbB2 (1245-1251) pY1248
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases and for epitope mapping of phosphosite-specific antibodies. The peptide sequence is located in the C-terminus of the kinase after the catalytic domain. Y1248 phosphorylation stimulates phosphotransferase activity. Phosphorylation regulates cell motility, cytoskeletal reorganization, transcription, intracellular location and molecular association.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: NPE-pY-LGL
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 883.87 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C