Product Name:
EGFR (1107-1113) pY1110
Product Number:
pe-04aza00
Peptide Name: EGFR (1107-1113) pY1110
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases and for epitope mapping of phosphosite-specific antibodies. The peptide sequence is located in the cytoplasmic region of the EGFR after the kinase catalytic domain. One of the major in vivo sites of phosphorylation in EGFR. Y1110 phosphorylation stimulates phosphotransferase activity and regulates transcription, protein conformation, intracellular location, receptor internalization, molecular association, and ubquitination.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: NPV-pY-HNQ
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 949.89 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C