Product Name:
EGFR (995-1001) pY998
Product Number:
pe-04ayz00
Peptide Name: EGFR (995-1001) pY998
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases and for epitope mapping of phosphosite-specific antibodies. The peptide sequence is located in the cytoplasmic region of EGFR after the kinase catalytic domain. Phosphorylation inhibits phosphotransferase activity. Phosphorylation also induces molecular association with CBL, CRK, CSK, SHC1, SHP-2 and STAT5A, as well as receptor internalization.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: SNF-pY-RAL
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 948.96 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C