Product Name:
B-Raf (443-449) pS446+pS447
Product Number:
pe-04ayt00
Peptide Name: B-Raf (443-449) pS446+pS447
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases and for epitope mapping of phosphosite-specific antibodies. The peptide sequence is located just before the kinase catalytic domain. This is the major in vivo phosphorylation sites in B-Raf. S446 and S447 phosphorylation stimulate phosphotransferase activity and induces interaction with H-Ras-1.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RRD-pS-pS-DD
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1008.76 Da
Peptide Purity Percent after Synthesis and Purification: <70
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C