Product Name:
Abl1 (249-256) pY253
Product Number:
pe-04aym00
Peptide Name: Abl1 (249-256) pY253
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases and for epitope mapping of phosphosite-specific antibodies. The peptide sequence is located in the protein kinase catalytic domain in and after subdomain I. Y253, Y257 and Y264 phosphorylation is predicted to be inhibitory for phosphotransferase activity. These phosphosites are located in and after the kinase subdomain I region, which is involved in binding the phosphates in the ATP substrate.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: GGQ-pY-GEV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 787.69 Da
Peptide Purity Percent after Synthesis and Purification: >70
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C