Product Name:
PKR (443-457) pT446+pT451+pY454+pS456
Product Number:
pe-04axb80
Peptide Name: PKR (443-457) pT446+pT451+pY454+pS456
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. T446 phosphorylation stimulates phosphotransferase activity. T451, Y454 and S456 phosphorylation are predicted to be inhibitory.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: GKR-pT-RSKG-pT-LR-pY-M-pS-P
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 2273.2 Da
Peptide Purity Percent after Synthesis and Purification: ~50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C