Product Name:
MEK3 (214-233) pS218+pT222+pY230
Product Number:
pe-04awi70
Peptide Name: MEK3 (214-233) pS218+pT222+pY230
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S218 and T222 phosphorylation stimulate phosphotransferase activity. Y230 phosphorylation is predicted to be inhibitory to catalytic activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: YLVD-pS-VAK-pT-IDAGCKP-pY-MAP
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 2597.9 Da
Peptide Purity Percent after Synthesis and Purification: >50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C