Product Name:
JAK2 (1004-1019) pY1007+pY1008+pS1016
Product Number:
pe-04avn65
Peptide Name: JAK2 (1004-1019) pY1007+pY1008+pS1016
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. Y1007 and Y1008 phosphorylation stimulate phosphotransferase activity. S1016 phosphorylation is predicted to be inhibitory to catalytic activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: DKE-pY-pY-KVKEPGE-pS-PIF
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 2384.5 Da
Peptide Purity Percent after Synthesis and Purification: ~50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C