Product Name:
DYRK1A (316-330) pY319+pY321+pS324+pY327
Product Number:
pe-04ata50
Peptide Name: DYRK1A (316-330) pY319+pY321+pS324+pY327
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. Y321 and probably Y319 phosphorylation stimulates phosphotransferase activity. S324 and Y327 phosphorylation are predicted to inhibit phosphotransferase activity. Thess phosphosits are located in the kinase activation loop between catalytic subdomains VII and VIII.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: QRI-pY-Q-pY-IQ-pS-RF-pY-RSP
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 2498.6 Da
Peptide Purity Percent after Synthesis and Purification: >50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C