Product Name:
CDK2 (155-163) pT158+pY159+pT160
Product Number:
pe-04ask95
Peptide Name: CDK2 (155-163) pT158+pY159+pT160
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The presentation as a dimer increases the potential activity. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. T158, Y159 and T160 phosphorylation stimulate phosphotransferase activity, and regulates cell cycle progression, chromatin organization and protein conformation.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: (PVR-pT-pY-pT-HEV-βA-Cys)2
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated, dimer
Peptide Molecular Mass Calculated: 3026.4 Da
Peptide Purity Percent after Synthesis and Purification: ~50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C