Product Name:
KIT (818-827) pS821+pY823
Product Number:
pe-04arm95
Peptide Name: KIT (818-827) pS821+pY823
Product Use: Blocking peptide for use with the Kit -S821+Y823 rabbit polyclonal antibody (Cat. No.: AB-PK674) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. S821 and Y823 phosphorylation stimulate phosphotransferase activity. Y823 phosphorylation also induces interaction with Grb2 and Grb7.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: KND-pS-N-pY-VVKG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1498.5 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: KIT - pS821+pY823 phosphosite-specific antibody (Cat. No.: AB-PK674)