Product Name:
EphA2 (585-591) pY588
Product Number:
pe-04alw99
Peptide Name: EphA2 (585-591) pY588
Product Use: Blocking peptide for use with the EphA2-pY588 rabbit polyclonal antibody (Cat. No.: AB-PK606) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the EphA2-TM domain located prior to the kinase catalytic domain. One of the major in vivo sites of phosphorylation in EphA2. Y588 phosphorylation stimulates phosphotransferase activity and regulates cell adhesion, cell differentiation, cell motility and molecular association, including inducing interaction with Nck1, VAV2 and VAV3.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: LKT-pY-VDP
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1089.13 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: EphA2 - pY588 phosphosite-specific antibody (Cat. No.: AB-PK606)