Product Name:
EGFR (1107-1113) pY1110
Product Number:
pe-04alu99
Peptide Name: EGFR (1107-1113) pY1110
Product Use: Blocking peptide for use with the EGFR-pY1110 rabbit polyclonal antibody (Cat. No.: AB-PK600) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the cytoplasmic region of the EGFR after the kinase catalytic domain. One of the major in vivo sites of phosphorylation in EGFR. Y1110 phosphorylation stimulates phosphotransferase activity and regulates transcription, protein conformation, intracellular location, receptor internalization, molecular association, and ubquitination.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: NPV-pY-HNQ
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1125.09 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: EGFR - pY1110 phosphosite-specific antibody (Cat. No.: AB-PK600)