Product Name:
CaMK2a (282-289) pT286
Product Number:
pe-04ajb90
Peptide Name: CaMK2a (282-289) pT286
Product Use: Blocking peptide for use with the CaMK2a-pT286 rabbit polyclonal antibody (Cat. No.: AB-PK555) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the region between the kinase catalytic domain and the CamKII-AD domains. The major site of in vivo phosphorylation of CaMK2a. T286 phosphorylation stimulates calcium/calmodulin-independent phosphotransferase activity and regulates cell growth, intracellular location, molecular association, including inducing interaction with GIT1 and MAP2, and inhibiting interaction with MBP and neurogranin.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: HRQE-pT-VDC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1137.1 Da
Peptide Purity Percent after Synthesis and Purification: 90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: CaMK2a - pT286 phosphosite-specific antibody (Cat. No.: AB-PK555)