Product Name:
B-Raf (443-450) pS446+pS447
Product Number:
pe-04aho99
Peptide Name: B-Raf (443-450) pS446+pS447
Product Use: Blocking peptide for use with the B-Raf-pS446+pS447 rabbit polyclonal antibody (Cat. No.: AB-PK534) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located just before the kinase catalytic domain. This is the major in vivo phosphorylation sites in B-Raf. S446 and S447 phosphorylation stimulate phosphotransferase activity and induces interaction with H-Ras-1.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RRD-pS-pS-DDW
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1369.19 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: B-Raf - pS446+pS447 phosphosite-specific antibody (Cat. No.: AB-PK534)