Product Name:
ERK2 (182-188) pT185+pY187
Product Number:
pe-04agd95
Peptide Name: ERK2 (182-188) pT185+pY187
Product Use: Blocking peptide for use with the ERK2-pT185+pY187 rabbit polyclonal antibody (Cat. No.: AB-PK622) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. T185 and Y187 phosphorylation stimulate phosphotransferase activity and regulates cell growth, cell motility, cytoskeletal reorganization, transcription, protein conformation, intracellular location, protein degradation, and molecular association.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: GFL-pT-E-pY-V
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1162.08 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: ERK2 - pT185+pY187 phosphosite-specific antibody (Cat. No.: AB-PK622)