Product Name:
PLCG1 (780-786) pY783
Product Number:
pe-04afd99
Peptide Name: PLCG1 (780-786) pY783
Product Use: Blocking peptide for use with the PLCG1-pY783 rabbit polyclonal antibody (Cat. No.: AB-PN530) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the intervening region between the second SH2 domain and the SH3 domain in PLCG1. This is one of the major sites of in vivo phosphorylation of PLCG1. Y783 phosphorylation stimulates phospholipase activity and regulates cell motility and molecular association, including inducing interaction with Grb2 and VEGFR-2.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: PGF-pY-VEA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1035.06 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PLCG1 - pY783 phosphosite-specific antibody (Cat. No.: AB-PN530)