Product Name:
EGFR (995-1001) pY998
Product Number:
pe-04acr99
Peptide Name: EGFR (995-1001) pY998
Product Use: Blocking peptide for use with the EGFR-pY998 rabbit polyclonal antibody (Cat. No.: AB-PK603) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the cytoplasmic region of EGFR after the kinase catalytic domain. Phosphorylation inhibits phosphotransferase activity. Phosphorylation also induces molecular association with CBL, CRK, CSK, SHC1, SHP-2 and STAT5A, as well as receptor internalization.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: SNF-pY-RAL
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1124.16 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: EGFR - pY998 phosphosite-specific antibody (Cat. No.: AB-PK603)