Product Name:
Bcr (174-180) pY177
Product Number:
pe-04ack99
Peptide Name: Bcr (174-180) pY177
Product Use: Blocking peptide for use with the Bcr-pY177 rabbit polyclonal antibody (Cat. No.: AB-PK538) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the N-terminal portion of the protein kinase. Y177 phosphorylation stimulates phosphotransferase activity. Phosphorylation induces interaction with Gab2, Grb2 and SOS1, and inhibits interaction with Hck.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: KPF-pY-VNV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1120.2 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: Bcr - pY177 phosphosite-specific antibody (Cat. No.: AB-PK538)