Product Name:
GSK3a (282-288) pY284+pY285
Product Number:
pe-04abu95
Peptide Name: GSK3a (282-288) pY284+pY285
Product Use: Blocking peptide for use with the GSK3a-pY284+Y285 rabbit polyclonal antibody (Cat. No.: AB-PK650) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. Y284 and Y285 phosphorylation is predicted to be inhibitory for phosphotransferase activity. These phosphosites are located in the kinase activation loop just before the catalytic subdomain VIII.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: SR-pY-pY-RAP
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1245.2 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: GSK3a - pY284+pY285 phosphosite-specific antibody (Cat. No.: AB-PK650)