Product Name:
PDLIM5-pY251
Product Number:
ab-pn522
Target Full Name: PDZ and LIM domain protein 5
Target Alias: ENH; ENH1; Enigma homolog; enigma-like LIM domain protein; Enigma-like PDZ and LIM domains protein; L9; LIM; PDLI5; PDLIM5; PDZ and LIM domain 5; PDZ and LIM domain protein 5
Product Type Specific: PDLIM5 (LIM) phosphosite-specific antibody
Antibody Code: PN522
Antibody Target Type: Phosphosite-specific
Antibody Phosphosite: Y251
Protein UniProt: Q96HC4
Protein SigNET: Q96HC4
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human PDLIM5 (LIM) sequence peptide Cat. No.: PE-04ADC99
Antibody Immunogen Sequence: TEF(pY)HVP(bA)C
Antibody Immunogen Description: Corresponds to amino acid residues T248 to P254; In the middle of the protein between the PDZ and first LIM domains. This is the mafor in vivo phosphorylation site of PDLIM5.
Production Method: Corresponds to amino acid residues T248 to P254; In the middle of the protein between the PDZ and first LIM domains. This is the mafor in vivo phosphorylation site of PDLIM5.
Antibody Modification: PDLIM5 (LIM) phosphosite-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 64-70 kDa.
Antibody Specificity: High-very high
Related Product 1: PDLIM5-pY251 blocking peptide
Scientific Background: PDLIM5 may play an important role in the heart development by scaffolding protein kinase C (PKC) to the Z-disk region. It may play a role in the regulation of cardiomyocyte expansion, since overexpression promotes the development of heart hypertrophy. It also regulates dendritic spine morphogenesis in neurons.
