Product Name:
EML4-pY226
Product Number:
ab-pn510
Target Full Name: Echinoderm microtubule-associated protein-like 4
Target Alias: C2orf2; DKFZp686P18118; echinoderm microtubule associated protein like 4; Echinoderm microtubule-associated protein-like 4; ELP120; EMAL4; EMAP-4; EMAPL4; EML4; FLJ10942; FLJ32318; Restrictedly overexpressed proliferation-associated protein; Ropp 120; ROPP120
Product Type Specific: EML4 phosphosite-specific antibody
Antibody Code: PN510
Antibody Target Type: Phosphosite-specific
Antibody Phosphosite: Y226
Protein UniProt: Q9HC35
Protein SigNET: Q9HC35
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human EML4 sequence peptide Cat. No.: PE-04AHG99
Antibody Immunogen Sequence: EGE(pY)IKM(bA)C
Antibody Immunogen Description: Corresponds to amino acid residues E223 to M229; In the N-terminal portion of EML4 near the HELP domain. This is the major in vivo phosphorylation site in EML4.
Production Method: Corresponds to amino acid residues E223 to M229; In the N-terminal portion of EML4 near the HELP domain. This is the major in vivo phosphorylation site in EML4.
Antibody Modification: EML4 phosphosite-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Potency: Very strong immunoreactivity with immunogen peptide on dot blots.
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 115-125 kDa.
Related Product 1: EML4-pY226 blocking peptide
Scientific Background: EML4 is a microtubule-binding protein that may modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
