Product Name:
Sgk223-pY413
Product Number:
ab-pk810
Target Full Name: Tyrosine-protein kinase SgK223; Homologue of rat pragma of Rnd2
Target Alias: FLJ00269; SG223; Sugen kinase 223
Product Type Specific: Protein kinase phosphosite-specific antibody
Antibody Code: PK810
Antibody Target Type: Phosphosite-specific
Antibody Phosphosite: Y413
Protein UniProt: Q86YV5
Protein SigNET: Q86YV5
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human Sgk223 sequence peptide Cat. No.: PE-04APO99
Antibody Immunogen Sequence: EPI(pY)AES(bA)C
Antibody Immunogen Description: Corresponds to amino acid residues E410 to S416; In the first third of the protein. This is the major in vivo site for phosphorylation of Sgk223.
Production Method: Corresponds to amino acid residues E410 to S416; In the first third of the protein. This is the major in vivo site for phosphorylation of Sgk223.
Antibody Modification: Protein kinase phosphosite-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Potency: Very strong immunoreactivity with immunogen peptide on dot blots.
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 150-170 kDa.
Related Product 1: Sgk223-pY413 blocking peptide
Scientific Background: SgK223 is a protein-serine/threonine kinase of the Other group and NKF3 family. It may regulate neurite outgrowth via activiation of RhoA (based on rat studies).
