Product Name:
RIOK1-pY466
Product Number:
ab-pk794
Target Full Name: Serine/threonine-protein kinase RIO1
Target Alias: AD034; BA288G3.1; FLJ30006; Kinase RIOK1; RIO kinase 1
Product Type Specific: Protein kinase phosphosite-specific antibody
Antibody Code: PK794
Antibody Target Type: Phosphosite-specific
Antibody Phosphosite: Y466
Protein UniProt: Q9BRS2
Protein SigNET: Q9BRS2
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human RIOK1 sequence peptide Cat. No.: PE-04APK01
Antibody Immunogen Sequence: NIL(pY)QTV(bA)C
Antibody Immunogen Description: Corresponds to amino acid residues N463 to V469; In the C-terminal third of the kinase after the catalytic domain. This is a major in vivo phosphorylation site in RIOK1.
Production Method: Corresponds to amino acid residues N463 to V469; In the C-terminal third of the kinase after the catalytic domain. This is a major in vivo phosphorylation site in RIOK1.
Antibody Modification: Protein kinase phosphosite-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 68-75 kDa.
Antibody Specificity: Very high
Antibody Cross Reactivity: No significant cross-reactive proteins detected in T98G cells.
Related Product 1: RIOK1-pY466 blocking peptide
Scientific Background: RIOK1 is a protein-serine/threonine kinase of the Atypical group and RIO family. It localizes to the nucleus. It exists as two alternatively spliced isoforms.
