Product Name:
PRKX-p T201+pT203
Product Number:
ab-pk785
Target Full Name: Serine/threonine-protein kinase PRKX
Target Alias: PKX1
Product Type Specific: Protein kinase phosphosite-specific antibody
Antibody Code: PK785
Antibody Target Type: Phosphosite-specific
Antibody Phosphosite: T201+T203
Protein UniProt: P51817
Protein SigNET: P51817
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human PRKX sequence peptide Cat. No.: PE-04APD99
Antibody Immunogen Sequence: VDR(pT)W(pT)LCG(bA)C
Antibody Immunogen Description: Corresponds to amino acid residues V198 to G206; In protein kinase catalytic domain activation T-loop between subdomains VII and VIII.
Production Method: Corresponds to amino acid residues V198 to G206; In protein kinase catalytic domain activation T-loop between subdomains VII and VIII.
Antibody Modification: Protein kinase phosphosite-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Potency: Strong immunoreactivity with immunogen peptide on dot blots.
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 38-44 kDa.
Related Product 1: PRKX-p T201+pT203 blocking peptide
Scientific Background: PRKX (PKX1) is a protein-serine/threonine kinase of the AGC group and PKA family. It can control cAMP signalling, cell differentiation, epithelial morphogenesis, nephrogenesis, and angiogenesis. Downstream targets of PRKX can include SMAD6, CREB, and PKD1. SMAD6 phosphorylation mediates differentiation of myeloid cells.
