Product Name:
MAK-pT157
Product Number:
ab-pk689
Target Full Name: Male germ cell-associated protein-serine kinase
Target Alias: Male germ cell-associated kinase
Product Type Specific: Protein kinase phosphosite-specific antibody
Antibody Code: PK689
Antibody Target Type: Phosphosite-specific
Antibody Phosphosite: T157
Protein UniProt: P20794
Protein SigNET: P20794
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human MAK sequence peptide Cat. No.: PE-04ADW90
Antibody Immunogen Sequence: PPY(pT)DYV(bA)C
Antibody Immunogen Description: Corresponds to amino acid residues P154 to V160; In protein kinase catalytic domain activation T-loop between subdomains VII and VIII.
Production Method: Corresponds to amino acid residues P154 to V160; In protein kinase catalytic domain activation T-loop between subdomains VII and VIII.
Antibody Modification: Protein kinase phosphosite-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Potency: Strong immunoreactivity with immunogen peptide on dot blots.
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 80-85 kDa.
Antibody Specificity: High-very high
Related Product 1: MAK-pT157 blocking peptide
Scientific Background: MAK is a protein-serine/threonine kinase of the CMGC group and RCK family. It has been associated with maintaining ciliary length and modulating long-term photoreceptor cell survival. MAK has been shown to phosphorylate FZR1 during different stages of cell cycle. MAK may have a role in prostate cancer chromosome stability and in spermatogenesis.
