Product Name:
BRD2-pS37
Product Number:
ab-pk547
Target Full Name: Bromodomain-containing protein-serine kinase 2
Target Alias: KIAA9001; O27.1.1; Protein RING3; RING3; A2AAU0; B0V072; B0V073
Product Type Specific: Protein kinase phosphosite-specific antibody
Antibody Code: PK546
Antibody Target Type: Phosphosite-specific
Antibody Phosphosite: S37
Protein UniProt: P25440
Protein SigNET: P25440
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human BRD2 sequence peptide Cat. No.: PE-04AIU99
Antibody Immunogen Sequence: RKP(pS)LLY(bA)C
Antibody Immunogen Description: Corresponds to amino acid residues R34 to Y40; Near the N-terminus of the protein.
Production Method: Corresponds to amino acid residues R34 to Y40; Near the N-terminus of the protein.
Antibody Modification: Protein kinase phosphosite-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Potency: Very strong immunoreactivity with immunogen peptide on dot blots.
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 90-110 kDa.
Antibody Specificity: Very high
Antibody Cross Reactivity: No cross-reactive proteins evident in sea star oocytes.
Related Product 1: BRD2-pS37 blocking peptide
Scientific Background: BRD2 is a protein-serine/threonine kinase of the Atypical group and BRD family. It is a transcriptional regulator that associates with transcription complexes and acetylated chromatin during mitosis. It plays a role in regulation of transcription through chromatin remodeling and nucleosome assembly. Mutations on multiple sites on BRD2 lead to loss of homodimerization.
