Product Name:
DUSP7-1
Product Number:
ab-np040-3
Target Full Name: Dual specificity protein phosphatase 7
Target Alias: Dual specificity protein phosphatase PYST2; DUS7; DUS7_HUMAN; PYST2
Product Type Specific: Protein phosphatase pan-specific antibody
Antibody Code: NP041-1
Antibody Target Type: Pan-specific
Protein UniProt: Q16829
Protein SigNET: Q16829
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human DUSP7 sequence peptide Cat. No.: PE-01BBD90
Antibody Immunogen Sequence: MKNQLRGPPARAHMC
Antibody Immunogen Description: Corresponds to amino acid residues M1 to M14; N-terminus
Production Method: Corresponds to amino acid residues M1 to M14; N-terminus
Antibody Modification: Protein phosphatase pan-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 1 µg/ml for immunoblotting
Antibody Species Reactivity: Human; Mouse
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 37-43 kDa.
Antibody Specificity: Medium
Related Product 1: DUSP7-1 blocking peptide
Related Product 2: DUSP7-2 pan-specific antibody (Cat. No.: AB-NP041-2)
Related Product 3: DUSP7-3 pan-specific antibody (Cat. No.: AB-NP041-3)
Scientific Background: DUSP7 (PYST2) is a dual specificity phosphatase that dephosphorylates MAP kinases on phospho-tyrosine and phospho- threonine residues and negatively regulates their phosphotransferase activity in response to changes in the cellular environment. PYST2-S may act as a negative regulator of PYST2-L, although it is unclear whether this is by competing for transcription, translation or activation factors.