Product Name:
DUSP5-3
Product Number:
ab-np039-2
Target Full Name: Dual specificity protein phosphatase 5
Target Alias: Dual specificity protein phosphatase hVH3; DUS5; DUS5_HUMAN; HVH3; VH3
Product Type Specific: Protein phosphatase pan-specific antibody
Antibody Code: NP039-3
Antibody Target Type: Pan-specific
Protein UniProt: Q16690
Protein SigNET: Q16690
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human DUSP5 (VH3) sequence peptide Cat. No.: PE-01BAZ90
Antibody Immunogen Sequence: CLKEAFDYIKQRRSMV
Antibody Immunogen Description: Corresponds to amino acid residues L286 to V300
Production Method: Corresponds to amino acid residues L286 to V300
Antibody Modification: Protein phosphatase pan-specific antibody
Antibody Concentration: 0.29 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Species Reactivity: Human; Mouse
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 40-42 kDa.
Antibody Specificity: Medium
Related Product 1: DUSP5-3 blocking peptide
Related Product 2: DUSP5-1 pan-specific antibody (Cat. No.: AB-NP039-1)
Related Product 3: DUSP5-2 pan-specific antibody (Cat. No.: AB-NP039-2)
Scientific Background: DUSP5 (VH3) is a dual specificity phosphatase that dephosphorylates MAP kinase ERK1 (and ERK2) on both 'T202' and 'Y204', and inhibits its activity during mitosis following initial growth factor activation.