Product Name:
DUSP3-1
Product Number:
ab-np023-5
Target Full Name: Dual specificity protein phosphatase 3
Target Alias: Dual specificity protein phosphatase VHR; DUS3; T-DSP11; VHR
Product Type Specific: Protein phosphatase pan-specific antibody
Antibody Code: NP030-2
Antibody Target Type: Pan-specific
Protein UniProt: P51452
Protein SigNET: P51452
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human DUSP3 (VHR) sequence peptide Cat. No.: PE-01BAR99
Antibody Immunogen Sequence: ELSVQDLNDLLSDGC
Antibody Immunogen Description: Corresponds to amino acid residues E6 to G19; N-terminus
Production Method: Corresponds to amino acid residues E6 to G19; N-terminus
Antibody Modification: Protein phosphatase pan-specific antibody
Antibody Concentration: 0.5 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 1 µg/ml for immunoblotting
Antibody Species Reactivity: Human; Mouse
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 20-25 kDa.
Antibody Specificity: Very high
Related Product 1: DUSP3-1 blocking peptide
Related Product 2: DUSP3-2 pan-specific antibody (Cat. No.: AB-NP030-3)
Related Product 3: DUSP3-3 pan-specific antibody (Cat. No.: AB-NP030-4)
Scientific Background: DUSP3 (VHR) exhibits phosphatase activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. It dephosphorylates and inactivates the MAP kinases ERK1 and ERK2.
