Product Name:
DUSP2-3
Product Number:
ab-np008-3
Target Full Name: Dual specificity protein phosphatase 2
Target Alias: Dual specificity protein phosphatase PAC-1
Product Type Specific: Protein phosphatase pan-specific antibody
Antibody Code: NP008-4
Antibody Target Type: Pan-specific
Protein UniProt: Q05923
Protein SigNET: Q05923
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human DUSP2 (PAC1) sequence peptide Cat. No.: PE-01BAQ80
Antibody Immunogen Sequence: CAWFQEAIGFIDWVKN
Antibody Immunogen Description: Corresponds to amino acid residues A234 to N248
Production Method: Corresponds to amino acid residues A234 to N248
Antibody Modification: Protein phosphatase pan-specific antibody
Antibody Concentration: 0.75 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 1 µg/ml for immunoblotting
Antibody Species Reactivity: Human; Mouse
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 31-34 kDa.
Antibody Specificity: High
Related Product 1: DUSP2-3 blocking peptide
Related Product 2: DUSP2-1 pan-specific antibody (Cat. No.: AB-NP008-2)
Related Product 3: DUSP2-2 pan-specific antibody (Cat. No.: AB-NP008-3)
Scientific Background: DUSP2 (PAC1) is a dual specificity phosphatase that dephosphorylates MAP kinase ERK2 (and ERK1) on both 'T183' and 'Y185', and inhibits its activity during mitosis following initial growth factor activation.