Product Name:
DUSP2-2
Product Number:
ab-np008-2
Target Full Name: Dual specificity protein phosphatase 2
Target Alias: Dual specificity protein phosphatase PAC-1
Product Type Specific: Protein phosphatase pan-specific antibody
Antibody Code: NP008-3
Antibody Target Type: Pan-specific
Protein UniProt: Q05923
Protein SigNET: Q05923
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human DUSP2 (PAC1) sequence peptide Cat. No.: PE-01BAP90
Antibody Immunogen Sequence: CLLPDRALRTRLVRG
Antibody Immunogen Description: Corresponds to amino acid residues C69 to G83
Production Method: Corresponds to amino acid residues C69 to G83
Antibody Modification: Protein phosphatase pan-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Species Reactivity: Human; Mouse
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 31-34 kDa.
Antibody Specificity: Medium
Related Product 1: DUSP2-2 blocking peptide
Related Product 2: DUSP2-1 pan-specific antibody (Cat. No.: AB-NP008-2)
Related Product 3: DUSP2-3 pan-specific antibody (Cat. No.: AB-NP008-4)
Scientific Background: DUSP2 (PAC1) is a dual specificity phosphatase that dephosphorylates MAP kinase ERK2 (and ERK1) on both 'T183' and 'Y185', and inhibits its activity during mitosis following initial growth factor activation.