Product Name:
DUSP1-3 (MKP-1)
Product Number:
ab-np006-2p
Target Full Name: MAP kinase phosphatase 1 (CL100, VH1)
Target Alias: 3CH134; CL100; DUS1; DUSP1; ERP; HVH1; PTPN10; PTPN16
Product Type Specific: Protein phosphatase pan-specific antibody
Antibody Code: NP006-3
Antibody Target Type: Pan-specific
Protein UniProt: P28562
Protein SigNET: P28562
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human DUSP1 (MKP1) sequence peptide Cat. No.: PE-01ATB99
Antibody Immunogen Sequence: CSWFNEAIDFIDSIKN
Antibody Immunogen Description: Corresponds to amino acid residues S235 to N249
Production Method: Corresponds to amino acid residues S235 to N249
Antibody Modification: Protein phosphatase pan-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 1 µg/ml for immunoblotting
Antibody Species Reactivity: Human; Mouse
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 39-44 kDa.
Antibody Specificity: Very low
Related Product 1: DUSP1-3 (MKP-1) blocking peptide
Related Product 2: DUSP1-1 (MKP-1) pan-specific antibody (Cat. No.: AB-NP006-4)
Related Product 3: DUSP1-2 (MKP-1) pan-specific antibody (Cat. No.: AB-NP006-2)
Related Product 4: DUSP1 (MKP-1) pan-specific antibody (Cat. No.: AB-NP006-2P)
Scientific Background: DUSP1 (MKP1) is a dual specificity phosphatase that dephosphorylates MAP kinase ERK2 (and ERK1) on both 'T183' and 'Y185', and inhibits its activity during the meiotic cell cycle.