Product Name:
KCNQ2
Product Number:
ab-nn275-1
Target Full Name: Potassium voltage-gated channel subfamily KQT member 2
Target Alias: BFNC; EBN1; ENB1; HNSPC; KCNA11; KQT like 2; KV7.2; KVEBN1. KvLQT2; voltage gated potassium channel subunit Kv7.2
Product Type Specific: Potassium channel pan-specific antibody
Antibody Code: NN275-1
Antibody Target Type: Pan-specific
Protein UniProt: O43526
Protein SigNET: O43526
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Antibody Immunogen Source: Fusion protein amino acids 1-59 of human KCNQ2
Antibody Modification: Potassium channel pan-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.09% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Immunohistochemistry | ICC/Immunofluorescence | Immunoprecipitation
Antibody Dilution Recommended: WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Antibody Potency: Medium-high potency. Detects a ~95 kDa protein in cell and tissue lysates by Western blotting.
Antibody Species Reactivity: Human | Mouse | Rat | Hamster
Antibody Positive Control: 1 µg/ml of SMC-308 was sufficient for detection of KCNQ2 in 10 µg of COS-1 cell lysate transiently expressing KCNQ2 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Antibody Specificity: Very high
Related Product 1: KCNQ1 pan-specific antibody (Cat. No.: AB-NN274-1)
Related Product 2: KCNQ4 pan-specific antibody (Cat. No.: AB-NN276-1)
Scientific Background: Kv7.2 (KvLQT2) is a potassium channel protein coded for by the gene KCNQ2. It is associated with benign familial neonatal convulsions (1).