Product Name:
Thorase/Atad1
Product Number:
ab-nn204-1
Target Full Name: ATPase family AAA domain-containing protein 1
Target Alias: ATAD1; AAA+ ATPase Thorase; Ab2-088; AFDC1; ATAD1_HUMAN; ATPase family; AAA domain containing 1; ATPase Thorase; AW107648; FLJ14600; FNP001; Thorase antibody
Product Type Specific: Thorase/Atad1 pan-specific antibody
Antibody Code: NN204-1
Antibody Target Type: Pan-specific
Protein UniProt: Q8NBU5
Protein SigNET: Q8NBU5
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Antibody Immunogen Source: Fusion protein amino acids 1-361 (Full length) of mouse Thorase
Antibody Modification: Thorase/Atad1 pan-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.09% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Immunohistochemistry | ICC/Immunofluorescence
Antibody Dilution Recommended: WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Antibody Potency: Medium-high potency. Detects a ~40 kDa protein in cell and tissue lysates by Western blotting.
Antibody Species Reactivity: Human | Mouse | Rat
Antibody Positive Control: 1 µg/ml of SMC-347 was sufficient for detection of Thorase in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Antibody Specificity: Medium-low
Scientific Background: Thorase, also known as Atad1 or ATPase family AAA domain-containing protein 1 is involved in synaptic plasticity, learning and memory through the regulation of the surface expression of AMPA receptors (AMPAR). Thorase is widely expressed with the highest expression in the brain and testis.