Product Name:
SGK1-NT
Product Number:
ab-nk294-1
Target Full Name: Serine-threonine-protein kinase Sgk1
Target Alias: Sgk1
Product Type Specific: Protein kinase pan-specific antibody
Antibody Code: NK294-1
Antibody Target Type: Pan-specific
Protein UniProt: O00141
Protein SigNET: O00141
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human SGK1 sequence peptide Cat. No.: PE-01BFG
Antibody Immunogen Sequence: MTVKTEAAKGTLTYSRMRGC
Antibody Immunogen Description: Corresponds to amino acid residues M1 to G19; N-terminus
Production Method: Corresponds to amino acid residues M1 to G19; N-terminus
Antibody Modification: Protein kinase pan-specific antibody
Antibody Concentration: 0.5 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 45-55 kDa.
Antibody Specificity: Very high
Antibody Cross Reactivity: No significant cross-reactivities detected in various human cancer cell lines, including A431, HEK-293, HeLa, HepG2, Jurkat and MCF7 cells, or in mouse brain, skeletal muscle, testes and thymus.
Related Product 1: SGK1-NT blocking peptide
Related Product 2: GSK3b (4-10) T7A, T8A, S9T; KinSub - Glycogen synthase kinase-3-beta-derived N-terminus (R4-F10, T7A, T8A, S9T, human) peptide; Akt1 protein kinase substrate peptide
Related Product 3: SGKSubtide - SGK1 protein kinase substrate peptide
Scientific Background: SGK (SGK1) is a protein-serine/threonine kinase of the AGC group and SGK family. It mediates membrane transports, ion channels, transcription factors, excitability of neurons, various cellular enzymes, cell survival, proliferation, growth, apoptosis, migration, and cellular stress response. It is activated by phosphorylation at T256 and S422.