Product Name:
PKG2-AcNMP2
Product Number:
ab-nk290-1
Target Full Name: cGMP-dependent protein kinase 2
Target Alias: cGK 2; cGKII; KGP2; Kinase cGMP-dependent protein kinase 2PKG2; PRKG2; PRKGR2; Protein kinase, cGMP-dependent, type II; Type II cGMP-dependent protein kinase
Product Type Specific: Protein kinase pan-specific antibody
Antibody Code: NK290-1
Antibody Target Type: Pan-specific
Protein UniProt: Q13237
Protein SigNET: Q13237
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human PKG2 (PRKG2) sequence peptide Cat. No.: PE-01BEW90
Antibody Immunogen Sequence: LQKYLEGYVANLNRDDEKRC
Antibody Immunogen Description: Corresponds to amino acid residues L397 to R415; Post-cNMP2
Production Method: Corresponds to amino acid residues L397 to R415; Post-cNMP2
Antibody Modification: Protein kinase pan-specific antibody
Antibody Concentration: 0.75 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 78-85 kDa.
Antibody Specificity: Medium-High
Antibody Cross Reactivity: Strong cross-reactivities for ~24, ~26 and~ 29 kDa proteins detected in mouse brain, testes and thymus. The ~24 and 26 kDa proteins were also strongly detected in human cancer cell lines, including A431, HEK-293, Jurkat and MCF7 cells.
Related Product 1: PKG2-AcNMP2 blocking peptide
Related Product 2: PKG2Subtide - PKG2 (PRKG2) protein kinase substrate peptide
Scientific Background: PKG2 (PRKG2) is a protein-serine/threonine kinase of the AGC group and PKG family. It is activated by cGMP. PKG2 may be a target in the treatment of colon cancer.