Product Name:
PCTK3-ANT
Product Number:
ab-nk286-1
Target Full Name: Cell division protein kinase 18; Protein-serine kinase PCTAIRE-3
Target Alias: CDK18; KPT3; PCTAIRE protein kinase 3; PCTK3; Serine/threonine-protein kinase PCTAIRE-3; ENSG00000117266
Product Type Specific: Protein kinase pan-specific antibody
Antibody Code: NK286-1
Antibody Target Type: Pan-specific
Protein UniProt: Q07002
Protein SigNET: Q07002
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human PCTK3 (PCTAIRE3, CDK18) sequence peptide Cat. No.: PE-01BEK65
Antibody Immunogen Sequence: CIEESLAEFTEQFNQLHNRR
Antibody Immunogen Description: Corresponds to amino acid residues I21 to R39; Post-N-terminus
Production Method: Corresponds to amino acid residues I21 to R39; Post-N-terminus
Antibody Modification: Protein kinase pan-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Potency: Strong immunoreactivity of a target-sized protein by Western blotting in various human cancer cell lines, including A431, HEK-293, HeLa, HepG2, Jurkat and MCF7 cells, and in mouse brain, testes and thymus.
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 50-55 kDa.
Antibody Specificity: Medium
Antibody Cross Reactivity: Strong cross-reactivities for ~110 and ~74 kDa detected in various human cancer cell lines, including A431, HEK-293, HeLa, HepG2, Jurkat and MCF7 cells. Medium-strong cross-reactivities with 5 proteins in mouse brain and testes and thymus.
Related Product 1: PCTK3-ANT blocking peptide
Scientific Background: PCTK3 (PCTAIRE3, CDK18) is a protein-serine/threonine kinase of the CMGC group and CDK family. It may play a role in terminally differentiated cells.
