Product Name:
MARK4-ANT
Product Number:
ab-nk277-1
Target Full Name: MAP/microtubule affinity-regulating protein-serine kinase 4
Target Alias: FLJ90097; KIAA1860; Kinase MARK4; MARKL1; MARKL1, Nbla00650; CCDS12658.1; ENSG00000007047
Product Type Specific: Protein kinase pan-specific antibody
Antibody Code: NK277-1
Antibody Target Type: Pan-specific
Protein UniProt: Q96L34
Protein SigNET: Q96L34
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human MARK4 sequence peptide Cat. No.: PE-01BDV80
Antibody Immunogen Sequence: CGSGRSSDKGPSWSSRSLGA
Antibody Immunogen Description: Corresponds to amino acid residues G22 to C40; Post-N-terminus
Production Method: Corresponds to amino acid residues G22 to C40; Post-N-terminus
Antibody Modification: Protein kinase pan-specific antibody
Antibody Concentration: 0.5 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 75-85 kDa.
Antibody Specificity: Very high
Antibody Cross Reactivity: No cross-reactivities detected in mouse brain, skeletal muscle, testes and thymus.
Related Product 1: MARK4-ANT blocking peptide
Related Product 2: MARK1-ANT pan-specific antibody (Cat. No.: AB-NK098-2)
Related Product 3: MARK1-pT215 phosphosite-specific antibody (Cat. No.: AB-PK694)
Related Product 4: MARK1-pT215 phosphosite-specific antibody (Cat. No.: AB-PK695)
Related Product 5: MARK2-ANT pan-specific antibody (Cat. No.: AB-NK275-1)
Related Product 6: MARK2-BCT pan-specific antibody (Cat. No.: AB-NK275-2)
Related Product 7: MARK3-ANT pan-specific antibody (Cat. No.: AB-NK276-1)
Related Product 8: MARK3-BCT pan-specific antibody (Cat. No.: AB-NK276-2)
Related Product 9: MARK3-pT507 phosphosite-specific antibody (Cat. No.: AB-PK697)
Related Product 10: MARK4-NT pan-specific antibody (Cat. No.: AB-NK277-2)
Scientific Background: MARK4 is a protein-serine/threonine kinase of the CAMK group and CAMKL family. It belongs to the microtubule-affinity regulating kinase (MARK) family and is primarily expressed in the brain and testis. It is associated with the centrosome during mitosis, it may also regulate the cell cycle progression. Mutation in this gene have been found in mouth and ovarian cancers.