Product Name:
CaMKK1 (CaMKK1-1)
Product Number:
ab-nk021-2
Target Full Name: Calcium/calmodulin-dependent protein-serine kinase kinase
Target Alias: Calcium/calmodulin-dependent protein kinase 1 alpha, isoform a; Calcium/calmodulin-dependent protein kinase kinase 1, alpha; CaMKK alpha protein; CaMKK1.; CaMKKA; DKFZP761M0423; KKCC1; MGC34095
Product Type Specific: Protein kinase pan-specific antibody
Antibody Code: NK022
Antibody Target Type: Pan-specific
Protein UniProt: Q8N5S9
Protein SigNET: Q8N5S9
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human CaMKK1 (CaMKK) sequence peptide
Antibody Immunogen Sequence: CGKSPELPGVQEDEA
Antibody Immunogen Description: Corresponds to amino acid residues G490 to A503; C-terminus
Production Method: Corresponds to amino acid residues G490 to A503; C-terminus
Antibody Modification: Protein kinase pan-specific antibody
Antibody Concentration: 1 mg/ml
Storage Buffer: 100 mM Tris-glycine, pH 7.0
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months, but either 0.1% sodium azide or 0.05% Thimerasol should be added. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Species Reactivity: Human; Rat
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 55-60 kDa.
Antibody Cross Reactivity: Cross-reacts with additional cross-reactive proteins in various rat tissues.
Related Product 1: CaMKK1-pS74 phosphosite-specific antibody (Cat. No.: AB-PK557)
Related Product 2: CaMKK1-pS74 phosphosite-specific antibody (Cat. No.: AB-PK557)
Scientific Background: CaMKK1 is a protein-serine/threonine kinase of the Other group and CaMKK family. It is a calcium/calmodulin-activated protein kinase that phosphorylates and activates CaMK1, CaMK1d, CaMK1g, CaMK4 and Akt1. Binding of calmodulin may releave intrasteric autoinhibition. It is partially inhibited upon phosphorylation by PRCAKA/PKA
