Product Name:

CaMK2g-PAD


Product Number:

ab-nk019-3

Price:

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$89.00
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Target Full Name: Calcium/calmodulin-dependent protein-serine kinase 2 gamma

Target Alias: Calcium/calmodulin-dependent protein kinase II gamma; CaM kinase II gamma subunit; CaMK2-gamma; CaMKG; CaMK-II gamma; CaMK-II gamma subunit; CaM-kinase II gamma; CaM-kinase II gamma chain; EC 2.7.11.17; Kinase CaMK2-gamma

Product Type Specific: Protein kinase pan-specific antibody

Antibody Code: NK020-1

Antibody Target Type: Pan-specific

Protein UniProt: Q13555

Protein SigNET: Q13555

Antibody Type: Polyclonal

Antibody Host Species: Rabbit

Antibody Immunogen Source: Human CaMK2g sequence peptide Cat. No.: PE-01BCJ90

Antibody Immunogen Sequence: CDGIKGSTESSNTTTEDEDL

Antibody Immunogen Description: Corresponds to amino acid residues D376 to L394; Before CaMAD, highly conserved in all CaMK2 isoforms

Production Method: Corresponds to amino acid residues D376 to L394; Before CaMAD, highly conserved in all CaMK2 isoforms

Antibody Modification: Protein kinase pan-specific antibody

Antibody Concentration: 0.5+0.28 mg/ml

Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol

Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.

Product Use: Western blotting | Antibody microarray

Antibody Dilution Recommended: 2 µg/ml for immunoblotting

Antibody Species Reactivity: Human

Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 55-60 kDa.

Scientific Background: CaMK2g is a protein-serine/threonine kinase of the CaMK group and CaMK2 family. It is a calcium/calmodulin-activated kinase that is involved in sarcoplasmic reticulum calcium transport, and may have a role in synaptic plasticity. Once activated by calcium or calmodulin CaMK2g will autophosphorylate at T287, and become activate in the absence of calcium.