Product Name:
PFTAIRE2-ANT
Product Number:
ab-nk004-2
Target Full Name: Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein
Target Alias: A2S7; AL2S7; ALS2CR7; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7; CDK15; PFTAIRE protein kinase 2; PFTK2; Serine/threonine-protein kinase ALS2CR7
Product Type Specific: Protein kinase pan-specific antibody
Antibody Code: NK004-2
Antibody Target Type: Pan-specific
Protein UniProt: Q96Q40
Protein SigNET: Q96Q40
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Human PFTAIRE2 (ALS2CR7) sequence peptide Cat. No.: PE-01BEO70
Antibody Immunogen Sequence: PETTEAAFKLTDLKEASC
Antibody Immunogen Description: Corresponds to amino acid residues P33 to C50; Post-N-terminus
Production Method: Corresponds to amino acid residues P33 to C50; Post-N-terminus
Antibody Modification: Protein kinase pan-specific antibody
Antibody Concentration: 0.5 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 0.05% Thimerasol
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Antibody microarray
Antibody Dilution Recommended: 2 µg/ml for immunoblotting
Antibody Potency: Very weak immunoreactivity of a target-sized protein by Western blotting in mouse skeletal muscle.
Antibody Species Reactivity: Human
Antibody Positive Control: The observed molecular mass of the processed target protein on SDS-PAGE gels is reported to be around 45-50 kDa.
Antibody Specificity: High-very high
Antibody Cross Reactivity: No significant cross-reactivities detected in various human cancer cell lines, including A431, HEK-293, HeLa, HepG2, Jurkat and MCF7 cells, or in diverse mouse tissues.
Related Product 1: PFTAIRE2-ANT blocking peptide
Related Product 2: PFTAIRE1-ANT pan-specific antibody (Cat. No.: AB-NK287-1)
Scientific Background: PFTAIRE2 (CDK15, PFTK2, ALS2CR7) is a protein-serine/threonine kinase of the CMGC group and CDK family. It controls cell cycle progression. PFTAIRE2 activity is mediated via a cyclin. PFTAIRE2 attenuates TRAIL induced apoptosis in part by phosphorylation of survivin at T34.
